摘要
目的：为观察异体胎儿真皮临床应用的可行性．方法：通过１９例经胰蛋白酶处理的冷冻异体胎儿真皮与自体表皮重组复合皮，并以单纯自体表皮为对照，作移植实验和动态观察．结果：复合皮移植后抗感染力强，成活率与自体表皮移植组无显著性差异（Ｐ＞０．０５），且可防止组织收缩和疤痕形成．同时提出异体胎儿真皮移植首先应满足血型的一致，否则对复合皮质量产生影响．结论：经胰蛋白酶处理的冷冻异体胎儿真皮可作自体表皮移植的载体，是理想的真皮替代物．临床应用异体胎儿真皮一次性完成复合皮移植术，提高了植皮外形效果，节省了患者的皮源，可以临床推广应用．
Objective: To observe the possibility of clinical application of allogeneic fetal dermis. Methods: Trypsin treated frozen allogeneic fetal dermis plus autologous epidermis ( n =19) was compared with autologous epidermis only in skin grafting by dynamic observation. Results: The results showed that composite skin (CS) graft, effective in anti infection and prevention of wound contraction and scar formation, had a living ratio almost as high as that of autologous epidermis graft ( P >0.05). To achieve high quality CS graft, blood group match was stressed in CS grafting with allogeneic fetal dermis. Conclusion: Trypsin treated frozen allogeneic dermis is an ideal substitute for dermis used as a carrier of autologous epidermis graft. As the graft, with high living ratio and good appearance, can be completed in one operation, CS graft of this sort could be widely put into clininal application.
出处
《第四军医大学学报》
1997年第5期461-463,共3页
Journal of the Fourth Military Medical University
关键词
烧伤
切痂创面
皮肤移植
胎儿
异体真皮
表皮
fetal autologous epidermis allogeneic dermis composite skin excisional wound
