摘要
以相转移催化法或在无水体系中合成了十个未见文献报道的２，３－二取代－５－氟脲嘧啶化合物，它们的结构经ＩＲ、１ＨＮＭＲ，元素分析或ＭＳ等确证。其中有些化合物具有一定的抗肿瘤活性。
Ten new 2,3 disubstituted 5 fluorouracil derivatives were prepared via phase transfer catalysis or in anhydrous system. Their structures were confirmed by IR, 1H NMR, elementary analysis or MS. The preliminary antitumor tests showed that some of the compounds exhibited certain activities.
出处
《合成化学》
CAS
CSCD
1997年第3期221-224,共4页
Chinese Journal of Synthetic Chemistry
关键词
氟脲嘧啶
抗癌化合物
相转移催化
抗癌药
Fluorouracil, Phase transfer catalysis, Antitumor compound, Synthesis.
