摘要
目的和方法：采用放射免疫法观察了２０例全麻和１５例硬膜外麻醉患者手术前１日、麻醉前、麻醉后和术毕红细胞内Ｃｕ－Ｚｎ－ＳＯＤ含量的变化。结果：以术前１日为对照，入手术室后麻醉前两组红细胞内Ｃｕ－Ｚｎ－ＳＯＤ含量均显著升高（Ｐ＜０．０１）。麻醉后及术毕，全麻组Ｃｕ－Ｚｎ－ＳＯＤ降至术前１日水平；硬膜外组虽有下降，但其值仍显著高于术前１日水平（Ｐ＜０．０５）。结论：麻醉前患者的精神紧张可引起红细胞内Ｃｕ－Ｚｎ－ＳＯＤ含量非常显著的增高，而麻醉和手术后Ｃｕ－Ｚｎ－ＳＯＤ含量下降与麻醉抑制了应激反应和Ｃｕ－Ｚｎ－ＳＯＤ消耗增加有关。提示手术中维持病人适当的应激能力可能对病人更为有利。
Objective:The Influence of preoperative stress, anesthesia and surgery on the CuZnSOD level of RBC was investigated in 20 general anesthesia patients (group A) and 15 epidural cases (group B). Methods: The CuZnSOD levels of RBC on the day before operation (base line), before anesthesia, after anesthesia and by the end of surgery were measured with immunoassay. Results: The SOD level of RBC was increased significantly before anesthesia compared with that on the day before operation in both groups (P<001). Conclusion: Preoperative stress plays a very important role in an increase of SOD of RBC.
出处
《临床麻醉学杂志》
CAS
CSCD
1997年第6期345-346,共2页
Journal of Clinical Anesthesiology
关键词
SOD
麻醉
外科手术
红细胞
SOD Stress General anesthesia Epidural blockade Operation
