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急性特发性血小板减少性紫癜患儿血清IL-6和IL-8的变化

The Changes of Serum Level of IL-6 and IL-8 in Children with Acute ITP
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摘要 目的探讨急性特发性血小板减少性紫癜(ITP)患儿血清IL-6、IL-8的变化及意义。方法采用酶联免疫法检测45例急性ITP患儿血清IL-6和IL-8水平。结果ITP患儿急性出血期IL-6、IL-8水平明显高于正常参考值。结论IL-6、IL-8在儿童ITP的发病中可能起重要作用。 Objective To determine the serum level of interleukin-6 (IL-6), interleukin-8 (IL-8), and research their significance in children patients with acute idiopathic thrombocytopenic purpura(ITP). Methods The serum of IL-6, IL-8 in 45 acute ITP patients were detected by enzyme-linked immunosorbent assay. Resuits The level of serum IL-6, IL-8 in actue ITP patients were higher than that of the control group. There were significant difference beween ITP group and control group. (P〈0.01). Conclusion Interleukin-6, interleukin-8 maybe take part in the pathogenesis of ITP.
出处 《南华大学学报(医学版)》 2008年第4期499-500,共2页 Journal of Nanhua University(Medical Edition)
关键词 血小板减少性紫癜 特发性 IL-6 IL-8 idiopathic thrombocytopenic purpura IL-6 IL-8
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