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COX-2、NSAIDs与肝癌 被引量:3

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摘要 COX-2mRNA和蛋白在HCC中呈普遍的高表达。COX-2可通过其抗凋亡、细胞周期阻滞、促进肿瘤细胞生长和肿瘤新生血管生成在HCC发生、发展过程中发挥作用。COX-2是防治HCC的重要分子靶点,大量的体内外实验证实NSAIDs能通过多种机制抑制HCC细胞的生长。
出处 《中华肝胆外科杂志》 CAS CSCD 2008年第8期587-589,共3页 Chinese Journal of Hepatobiliary Surgery
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