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巢蛋白在垂体和垂体腺瘤中表达的研究进展

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摘要 巢蛋白(nestin)是第Ⅵ类中间丝蛋白,主要在胚胎期神经前体细胞和神经干细胞一过性表达。在正常细胞演变成肿瘤细胞过程中,巢蛋白又呈现返祖性表达。近年来研究发现nestin阳性细胞散在的分布于垂体的前叶、中间部和神经部。但这些nestin阳性细胞是否包括了垂体前体细胞还不清楚。在垂体腺瘤的部分毛细血管内皮细胞中也检测到nestin的表达,推测它可作为垂体血管发生的一种检测指标。
出处 《解剖学研究》 CAS 2008年第4期303-306,共4页 Anatomy Research
基金 广东省科技计划资助项目(2007B031504002)
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参考文献26

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