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谷胱甘肽的水平及氧化还原状态与炎症性肠病的关系 被引量：5

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摘要 氧化还原反应（redox reactions）是细胞新陈代谢和动态平衡中的一个完整的部分。在氧化还原反应中产生亲电子副产物是不可避免的,而且细胞要消耗相当多的能量用于合成许多蛋白质及利用内源性和食物中的抗氧化物,
作者 王英 罗敏 李卉 张静 张菁 魏巍 高娃 李嵘 邓馨
机构地区 武警总医院南一科 中国协和医科大学协和医院消化内科
出处 《实用医学杂志》 CAS 2008年第17期3079-3081,共3页 The Journal of Practical Medicine
关键词 氧化还原状态 炎症性肠病 谷胱甘肽 氧化还原反应 新陈代谢 抗氧化物 多蛋白质 水
分类号 R574.6 [医药卫生—消化系统]
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参考文献19

  • 1Lu S C. Regulation of glutathione synthesis [J]. Curr Top Cell Regul, 2000, 36(7) : 95-116.
  • 2Jones D P. Redox potential of GSH/GSSG couple: assay and biological significance [J]. Methods Enzymol, 2002, 348(16):93-112.
  • 3Bella D L, Hirschberger L L, Hosokawa Y, et al. Mechanisms involved in the regulation of key enzymes of cysteine metabolism in rat liver in vivo[J]. Am J Physiol, 1999, 276(2): 326-335.
  • 4Meister A. Glutathione metabolism [J]. Methods Enzymol, 1995, 251: 3-7.
  • 5Droge W, Breitkreutz R. Glutathione and immune function [J]. Proc Nutr Soc, 2000, 59(4): 595-600.
  • 6Ward N E, Pierce D S, Chung S E, et al. Irreversible inactivation of protein kinase C by glutathione[J]. J Biol Chem, 1998, 273(20) : 12558-12566.
  • 7Hamuro J, Murata Y, Suzuki M. The triggering and healing of tumor stromal latinflammation reactions regulated by y oxidative and reductive macrophages [J]. Gann Monograph Cancer Res, 1999, 48 (5) : 153-164.
  • 8Peterson J D, Herzenberg L A, Vasquez K, et al. Glutathione levels in antigen- presenting cells modulate Thl versus Th2 response patterns[J]. Proc Nail Acad Sci U S A, 1998, 95(6): 3071-3076.
  • 9Jeannin P, Delneste Y, Lecoanet-Henchoz S, et al. Thiols decrease human interleukin (IL) 4 production and IL-4-induced immunoglobulin synthesis [J]. J Exp Med, 1995, 182(6): 1785-1792.
  • 10Lakshminarayanan V, Drab-Weiss E A, Roebuck K A. H2O2 and tumor necrosis factor-alpha induce differential binding of the redox-responsive transcription factors AP-1 and NF-kappaB to the interleukin-8 promoter in endothelial and epithelial cells [J]. J Bio Chem, 1998, 273(49) : 32670- 32678.

二级参考文献69

  • 1白爱平.炎症性肠病发病机制的微生物因素[J].世界华人消化杂志,2006,14(7):645-649. 被引量：28
  • 2Konrad A, Mahler M, Flogerzi B, Kalousek MB, Lange J, Varga L, Seibold F. Amelioration of murine colitis by feeding a solution of lysed Escherichia coli. Scand J Gastroenterol 2003;38:172-179.
  • 3Villegas I, Alarcon de la Lastra C, Orjales A, La Casa C. A new flavonoid derivative, dosmalfate, attenuates the development of dextran sulphate sodium-induced colitis in mice. Int Immunopharmacol 2003;3:1731-1741.
  • 4Murata Y, Amao M, Yoneda J, Hamuro J. Intracellular thiol redox status of macrophages directs the Th1 skewing in thioredoxin transgenic mice during aging. Mol Immunol 2002;38:747-757.
  • 5Zea-Iriarte WL, Makiyama K, Goto S, Murase K, Urata Y, Sekine I, Hara K, Kondo T. Impairment of antioxidants in colonic epithelial cells isolated from trinitrobenzene sulphonic acid-induced colitis rats. Protective effect of rebamipide. Scand J Gastroenterol 1996;31:985-992.
  • 6Romagnani P, Annunziato F, Piccinni MP, Maggi E, Romagnani S. Th1/Th2 cells, their associated molecules and role in pathophysiology. Eur Cytokine Netw 2000;11:510-511.
  • 7Peterson JD, Herzenberg LA, Vasquez K, Waltenbaugh C. Glutathione levels in antigen-presenting cells modulate Th1 versus Th2 response patterns. Proc Natl Acad Sci USA 1998;95:3071-3076.
  • 8Murata Y, Ohteki T, Koyasu S, Hamuro J. IFN-gamma and pro-inflammatory cytokine production by antigen-presenting cells is dictated by intracellular thiol redox status regulated by oxygen tension. Eur J Immunol 2002;32:2866-2873.
  • 9Jeannin P, Delneste Y, Aubry JP, Lecoanet-Henchoz S, Gauchat JF, Life P, Bonnefoy JY. Thiols decrease human IL-4 production and IL-4-induced immunoglobulin synthesis. Int Arch Allergy Immunol 1997;113:329-330.
  • 10Goldin E, Ardite E, Elizalde JI, Odriozola A, Panes J, Pique JM, Fernandez-Checa JC. Gastric mucosal damage in experimental diabetes in rats: role of endogenous glutathione. Gastroenterology 1997;112:855-863.

共引文献56

同被引文献52

  • 1张艰,李圣青,李焕章,戚好文,吴昌归.NF-κB在大鼠急性肺损伤模型肺组织中的表达及N-乙酰半胱氨酸的影响[J].细胞与分子免疫学杂志,2004,20(6):712-715. 被引量：19
  • 2邹朝霞,何志义,冉丕鑫.吸烟对大鼠肺内谷胱甘肽与γ-GCS的影响及乙酰半胱氨酸的干预作用[J].中国病理生理杂志,2007,23(1):86-89. 被引量：10
  • 3Melamed A,Sorvillo FJ.The burden of sepsis-associated mortality in the United States from 1999 to 2005:an analysis of multiple-cause-of-death data[J].Critical Care,2009,13(1):R28.
  • 4Poll T,Steven M.Host-pathogen interactions in sepsis[J].Lancet Infect Dis,2008,8(1):32-43.
  • 5Krouzecky A,Matejovic M,Radej J,et al.Perfusion pressure manipulation in porcine sepsis:effects on intestinal hemodynamics[J].Physiol Res,2006,55(5):527-33.
  • 6Wiest R,Rath HC.Bacterial translocation in the gut[J].Best Practice & Research Clinical Gastroenterology,2003,17(3):397-425.
  • 7Ince C.The microcirculation is the motor of sepsis[J].Crit Care,2005,9:S13-9.
  • 8Bone RC.Immunologic Dissonance:A Continuing Evolution in Our Understanding of the Systemic Inflammatory Response Syndrome (SIRS) and the Multiple Organ Dysfunction Syndrome (MODS)[J].Ann Intern Med,1996,125(8):680-7.
  • 9Poll T.Tissue factor as an initiator of coagulation and inflammation in the lung[J].Crit Care,2008,12:S3.
  • 10Serracino-Inglott F,Virlos IT,Habib NA,et al.Differential nitric oxide synthase expression during hepatic ischemia reperfusion[J].Am J Surg,2003,185(6):589-95.

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实用医学杂志
2008年 第17期

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