摘要
[目的]探讨中药疏肝健脾方治疗反流性食管炎(RE)的临床疗效。[方法]符合纳入条件的120例患者随机分为2组,治疗组予疏肝健脾方,早晚分服;对照组口服莫沙比利5 mg,3次/d,奥美拉唑20 mg,2次/d,疗程均为4周。[结果]与对照组比较,治疗组在提高食管下端括约肌张力及对pH值影响差异均有统计学意义(均P<0.05)。[结论]疏肝健脾方具有提高食管下端括约肌张力,改善反流的作用。
[Objective]To observe the clinical effects of Shuganjianpi prescription in the treatment of reflux esophagitis. [Methods]One hundred and twenty patients who suffered from reflux esophagitis were divided into two groups randomly. The treatment group were treated with Shuganjianpi prescription （to add or substract,）twice a day, the control group were treated with mosabilium 5mg orally 15 min before meals and omeprazole 20mg bid,for 4 weeks as a course. [Results] Compared with the control group, the treatment group can increase the tensile of lower esophageal sphincter and make the remarkable difference in the pH values（ P〈 0. 05）. [Conclusion ] Shuganjianpi Prescription can increase the tensile of lower esophageal and improve the sympton of reflux esophagitis. The treatment group is more effective than the control group.
出处
《中国中西医结合消化杂志》
CAS
2008年第4期224-225,228,共3页
Chinese Journal of Integrated Traditional and Western Medicine on Digestion
基金
广东省中医药局资助项目(2007280)
关键词
疏肝健脾方
反流性食管炎
食管下端括约肌静息压
PH值
shuganjianpi prescription
reflux esophagitis
the resting prossure of inferior esophageal sphincter
pH values.
