摘要
目的观察咳喘宁对支气管哮喘患者外周血白细胞计数的影响。方法采用随机临床对照观察方法,咳喘宁治疗152例为治疗组,以桂龙咳喘宁胶囊治疗146例为对照组,观察两组患者治疗前后症状评分,嗜酸粒细胞、淋巴细胞、中性粒细胞计数的变化,并比较两组的临床疗效。结果与治疗前比较,治疗后两组白天及夜间哮喘症状评分、嗜酸粒细胞计数明显下降(P<0.01),淋巴细胞、中性粒细胞计数差异均无统计学意义(P>0.05);治疗组治疗后白天及夜间哮喘症状评分低于对照组(P<0.01),临床总有效率为98.6%,明显优于对照组89.0%(P<0.01)。结论咳喘宁可减少嗜酸粒细胞计数,改善慢性炎症反应,疗效优于桂龙咳喘宁胶囊。
Objective To observe the effect of Kechuanning on peripheral white blood cells of patients with bronchial asthma. Methods Randomly clinical observation method was adopted, the treatment group（ n = 152） were treated with Kechuanning, and the control group （n = 146） were treated with Guilongkechuanning capsule ; The symptom score, the count of eosinophils, leukomonocyte and neutrophile granulocyte, and clinical therapeutic effect were observed. Results Compared with before-treatment, the day and night symptom score, the count of eosinophils were decreased in both groups after-treatment（P 〈 0. 01 ）, the count of leukomonocyte and neutrophile granulocyte in both group have no statistical significance （ P 〉 0. 05 ） ; The symptom score of treatment group were decreased compared with control group. The total effective rate of treatment group was 98. 6%, which was higher than that of control group（ 89.0%, P 〈 0.01 ）. Conclusion The Kechuanning could decrease the count of eosinophils and improve the chronic inflammatory reaction, and therapeutic effect is super to that of Guilongkechuanning capsule.
出处
《中国现代药物应用》
2008年第17期1-3,共3页
Chinese Journal of Modern Drug Application
基金
河北省科技攻关计划项目(06276102D-37)
