摘要
目的评估超声方法测量心踝指数（CAVI）的准确性和可重复性，以及它与振荡法CAVI之间的相互关系，分析CAVI与颈动脉弹性指标的关系。方法选取进行年度体检者96人（男性64人），年龄22—62岁，平均年龄（41．2±8．9）岁，使用M型及多普勒法分别测量主动脉．踝动脉的脉搏波传导速度（eaPWV），经公式计算可分别得出M型心踝指数（CAVIm）和多普勒法心踝指数（CAVId）。使用全自动动脉硬化检测设备测量CAVI。在96人中随机抽取20人进行重复性测量：观察者间重复性：每个对象由2名观察者（观察者1和观察者2）以随机顺序进行CAVIm和CAVId测量，两侧测量之间至少相隔5min。观察者内可重复性：每个对象由观察者1进行2次测量，2次测量之间相隔1d。结果M型和多普勒法测得的CAVIm和CAVId与振荡法测得的CAVI有良好的相关性（r1=0．925，r2=0．738，P〈0．001）。观察者内和观察者间CAVIm和CAVId的可重复性Pearson相关显著，单变量分析结果表明，CAVI、CAVIm和CAVId均和内中膜厚度（IMT）、僵硬度指数（13）显著相关。结论超声方法为无创简便地测量CAVI提供了一种新的方法，用于评价大动脉弹性功能可重复性好，与振荡法CAVI显著相关。
Objective The cardio-ankle vascular index （CAVI） could be obtained by measuring pulse wave velocity （PWV） and blood pressure （BP）. This method is associated with various technical drawbacks. We evaluated the accuracy and usefulness of CAVI measured by ultrasound via detecting the aortic and ankle flow directly by ultrasonic probe. Methods CAVI was determined in 96 subjects [ 64 male, mean age （41.2 ±8.9） years] who took part in the annual check up program in our department by means of the professional equipment （BP-203RPE 11 ,VP-1000, Japan, CAVIp）, the M-mode （CAVIm） and color Doppler flow imaging （CAVId）. Measurement reproducibility on was obtained by repeat the measurements in 20 subjects choose randomly from the 96 subjects. Carotid ultrasound （CU） was performed to obtain intimamedia thickness （IMT） and 13 index in all subjects. Results CAVI obtained by various methods were similar and comparable （ CAVIm 7. 74 ± 1.62, CAVId 7. 77 ± 1.59, CAVIp 8. 74 ± 1.57, all P 〉 0. 05 ）. Inter-group and inter-observer variance was negligible （ r1 = 0. 98, r2 = 0.97 ）. There were also significant correlations between CAVIm and IMT, CAVIm and 13 （ r1 = 0. 824, r2 = 0. 812, all P 〈 0. 01 ）, and between CAVId and IMT, CAVId and 13 （r1 =0.815, r2 =0.813, all P 〈0.01）. Conclusions CAVI could be correctly measured by ultrasound technique.
出处
《中华心血管病杂志》
CAS
CSCD
北大核心
2008年第8期750-753,共4页
Chinese Journal of Cardiology
关键词
动脉硬化
血管
弹性
超声检查
Arteriosclerosis
Blood vessels
Elasticity
Ultrasonography
