摘要
目的:了解小儿肺炎患者中产超广谱β-内酰胺酶(ESBLs),不产超广谱β-内酰胺酶的肺炎克雷伯菌的耐药分析。方法:依据MicroScan4微生物分析仪上测得各抗生素MIC值,确证试验用纸片扩散法。结果:产ESBLs肺炎克雷伯菌检出率达77.6%,耐药情况严重。结论:小儿感染肺炎克雷伯菌的耐药现象严重,多重耐现象突出,尤其ESBLs检出率高。亚胺培南仍是治疗产ESBLs菌的首选药物,选用丁胺卡那或环丙沙星时最好在血药浓度监测下使用。
Objective：To investigate the analysis to the drug-resistance of the pneumonia Klebsiella producing the extended spectrumβ-lactamase （ESBLs） and non-producing the ESBLs to the infants. Method： According to antibiotic MIC value measured by the MicroScan 4 microorganism analyzer, we can confirm that the experiment should use the scrip spreading method. Result： The relevance ratio of the pneumonia Klebsiella producing the ESBLs was up to 77.6%, and the phenomenon of the drug-resistance was very serious. Conclusion： The phenomenon of the drug-resistance which the infants are infected by the pneumonia Klebsiella is very serious. The phenomenon of multidrug resistance is very evident; especially the relevance ratio of ESBLs is very high. Imipenum is still the preferred drug of treating produce ESBLs. Being treated by Amikacin and ciprofloxacin, with the monitor of blood concentration is the best way.
出处
《安徽卫生职业技术学院学报》
2008年第4期90-91,共2页
Journal of Anhui Health Vocational & Technical College
关键词
小儿肺炎克雷伯茵超光谱B-内酰胺酶耐药性
the infants
the pneumonia Klebsiella
the extended spectruml3-1actamase （ESBLs）
the drug-resistance
