摘要
目的:回顾性的对照研究评估窒息新生儿肾衰发生率、肾衰形式、严重性与Apgar评分、缺氧缺血性脑病(HIE)的相互关系。方法:63例窒息的新生儿为研究组,25例健康的新生儿为对照组。评估新生儿的尿量,尿镜检,生化参数,肾脏超声。结果:研究组和对照组比较,血尿素氮、肌酐显著增高(P<0.001);尿量在两组之间没有显著的差异。63例窒息的新生儿30例(47.6%)有肾衰,其中非少尿型(24/30),少尿型(6/30)。6个月后所有的新生儿各项检查均正常。结论:新生儿窒息合并肾衰是一个重要的临床问题,大多数肾衰为非少尿型。少尿,低钠血症,异常的肾脏超声预后不良。
Objective： To make a retrospective study on the relationships among the incidence rate of renal failure in asphyxiated neonates, type of renal failure and severity, and Apgar score and hypoxic ischemic encephalopathy （HIE） grading of the neonates. Methods： eighy-five neonates were divided into two groups-63 asphyxiated babies as study group and 25 healthy as control group. Renal functions were assessed by using urinary output, urine microscopy, biochemical parameters and sonographic findings. Results： Blood urea and serum creatinine were significantly higher in asphyxiated babies than those in the control group （P〈0.001）. There was no significant difference in urine output between the control and the study group. Of the 63 asphyxiated babies, 30（47.6%） had renal failure, which was of the non-oliguric type in （24/30） cases and oliguric type in （6/ 30） cases. Renal parameters were normalized in all neonates by 6 months of age. Conclusions： renal failure is a significant problem in asphyxiated neonates with majority of babies having non-oliguric failure. Oliguria, hyponatremia and abnormal sonographic scan are bad prognostic signs in renal failure secondary to birth asphyxia.
出处
《安徽卫生职业技术学院学报》
2008年第4期20-21,共2页
Journal of Anhui Health Vocational & Technical College
关键词
出生窒息
缺氧缺血性脑病
肾衰
Birth asphyxia
Hypoxic ischemic encephalopathy
Renal failure
