摘要
报道口服潘生丁治疗61例婴幼儿呼吸道合胞病毒肺炎的疗效。结果显示,潘生丁组发热、咳嗽、喘憋、哮鸣音及湿罗音的持续时间和总病程明显短于对照组(P<0.05-0.01);发病3天内用药组总病程明显短于发病3天后用药组。提示潘生丁有缓解呼吸道合胞病毒肺炎的病情和缩短病程的作用;早期用药疗效更好。治疗量的潘生丁未发现明显副作用。
This article reports the efficacy of dipyridamole in treatment of infants suffering from respiratory syncytial virus pneumonia. Of 61 infants,32 randomly selected patients were treated with dipyridamole in addition to the general therapy and 29 controlled patients were treated only with general therapy. The dosage of dipyridamole was given 3-5 mg/kg of body weight daily, divided in 2-3 doses by oral route for 5 days. The results showed that the duration of fever, cough, gasp for breath, wheezing and moist rales, the course of the disease in dipyridamole group were significantly shorter than those in control group (P<0. 05-0. 01). The patients, receiving dipyridamole within the first 3 days following onset, appeared to exert a shorter course of illness than patients receiving the drug after 3 days of the onset. These data showed that dipyridamole can improve the clinical manifestations and shorten the course of the disease. It is suggested that the efficacy of the drug will be better if it can be given earlier. No evident side-effects of the drug were observed.
出处
《湖南医科大学学报》
CSCD
1990年第4期375-377,共3页
Bulletin of Hunan Medical University
关键词
RSV
双哌达莫
肺炎
潘生丁
dipyridamole
respiratory syncytial virus
pneumonia
drug therapy
thera- peutic use
