摘要
目的:探讨白介素-4(IL-4)、白介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)在生殖器疱疹发病机理中的作用。方法:采用酶联免疫吸附试验,测定60例生殖器疱疹患者及60例正常人血清IL-4、IL-6、TNF-α含量。结果:生殖器疱疹患者血清IL-6水平低于正常对照组(P<0.05),而IL-4、TNF-α水平高于正常对照组(P<0.05)。结论:生殖器疱疹患者体内存在细胞因子表达异常是导致生殖器疱疹反复发作的原因之一。
Objective：To study the role of interleukin-4 （IL-4）,interleukin-6 （IL-6） and tumor necrosis factor-α （TNF-α）in the pathogenesis of genital herpes. Methods：The serum levels of IL-4,IL-6 and TNF-α were determined by enzyme-linked immunosorbent assay in 60 patients with genital herpes and 60 health people. Results：The serum level of IL-6 was significantly lower in the patients with genital herpes than that of the normal controls （P〈0.05）,but the serum levels of IL-4 and TNF-αwere significantly higher in the patients with genital herpes than those of the normal controls （P〈0.05）.Conclusion：The abnormal cell factor expression in the patients with genital herpes cytolysis could be an important reason in the recurrence of the disease.
出处
《现代医药卫生》
2008年第17期2562-2563,共2页
Journal of Modern Medicine & Health
关键词
生殖器疱疹
IL-4
IL-6
TNF—α
Genital herpos
Interleukin-4
Interleukin-6
Tumor Necrosis factor-α
