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细胞融合和非整倍体的产生 被引量：2

Production of Cell Fusion and Generation of Aneuploidy
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摘要 肿瘤发生的具体机制尚未定论。近来研究发现,病理情况下细胞间发生融合形成的四倍体等多倍体细胞,其作为非整倍体的中间过度状态在肿瘤的发生过程中发挥了很大作用,提示细胞融合可能是肿瘤发生的一种机制。本文就细胞融合、非整倍体及肿瘤三者之间的关系作一简要阐述。 The mechanism of tumor formation is not completely understood. Recent studies demonstrated that polyploidy especially tetraploid formed by cell fusion was believed to play a critical role in the genesis and development of tumor as the intermediate state of aneuploidy. These suggested that cell fusion maybe one mechanism of the tumor genesis. This article reviews the relationship amony cell fusion, aneuploidy and tumor.
作者 陈辉 杨立业
机构地区 汕头大学医学院神经外科学
出处 《医学综述》 2008年第17期2561-2564,共4页 Medical Recapitulate
基金 国家自然科学基金(30672359)
关键词 细胞融合 染色体 非整倍体 肿瘤 Cell fusion Chromosome Aneuploidy Tumor
分类号 R73 [医药卫生—肿瘤]
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参考文献21

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同被引文献28

  • 1莫文健,毛平,何秋山,应逸,朱志刚,许艳丽,杜庆华.两步法脐血巨核细胞体外扩增的研究[J].中国输血杂志,2005,18(5):381-383. 被引量：1
  • 2方建培,夏婷,陈国华,吴燕峰,徐宏贵,魏菁,黄绍良.脐血和外周血来源的巨核细胞体外扩增差异的研究[J].中华儿科杂志,2006,44(11):869-872. 被引量：3
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医学综述
2008年 第17期

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