摘要
腹腔注射桃核承气汤６ｇ／ｋｇ能预防利多卡因的毒性，降低小鼠的死亡率，并增加大鼠对利多卡因的耐受量，预防利多卡因毒性的半数有效量为（５．３５±０．０８）ｇ／ｋｇ，且其预防作用与其剂量，呈显著的量效关系。
It has been demonstrated that THCQT (6 g/kg, ip) has an effect in preventing the lidocaine′s toxicity and prolonging the survival time in rats; its ED50 is (5 35±0 8) g/kg and this effect varies with the dosages in use.THCQT can significantly increase the tolerance to lidocaine in rats.
