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类风湿性关节炎患者血清新喋呤、可溶性IL-2R的测定及临床意义

Studies Neopterin, Soluble Interleukin-2 Receptor in Serum on Rneumatoid Arthritis
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摘要 为早期诊断类风湿性关节炎,提高治愈率,降低致残率,笔者检测了142例类风湿性关节炎患者和200例献血员(对照组)血清新喋呤、可溶性IL-2R水平.结果表明:142例类风湿性关节炎患者组的血清新喋呤和可溶性IL-2R水平分别为26.12±0.94ng/ml和435.43±22.59μ/ml,而对照组仅为<10ng/ml和<250μ/ml.经统计学检验.两者呈显著性差异(P<0.001),提示血清新喋呤、可溶性IL-2R测定可用于早期鉴别急性类风湿性关节炎的诊断. Neopterin (NPT), soluble interleukin-2 receptor (SIL-2R) in serum have beendetermined by an enzyme linked immunosorbent assay (ELISA) in 142 specimens in order to research thesensible mark in earily diagnosis rheumatoid arthritis (RA). As a control group, 200 donators were alsoobserved. The result showed that NPT and SIL-2R respectively were 26.16 ±0.94ng/ml, 435.43±22.59μ/ml in RA. Below 10ng/ml, 250μ/ml in normal controls, NPT and SIL-2R were significantlyrising in RA (P<0.001). This work comes to the conclusion that NPT. SIL-2R may be play animportant roles in the diagnosis of acute RA.
出处 《伤残医学杂志》 1997年第2期24-25,共2页 Medical Journal of Trauma and Disability
关键词 类风湿性关节炎 新喋呤 可溶性IL-2R 测定 Rheumatoid arthritis Neopterin Soluble interleukin-2 receptor
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