摘要
目的:了解不同海拔地区藏族中、青年心脏疾病与高血压患病情况以及与高血压有关的降钙素基因相关肽和胰岛素样生长因子Ⅱ水平。方法:采用流行病学方法,调查研究不同海拔地区藏族中、青年心脏病和高血压患病情况,采用放射免疫法测定与高血压相关因素。结果:不同海拔地区藏族中、青年心脏疾病与高血压患病情况均有显著性差别(P<0.05);高血压和心脏病患病率分别10.01%和13.97%,男性患病率高于女性,不同海拔藏族中、青年高血压患者降钙素基因相关肽和胰岛素样生长因子Ⅱ水平均有显著性差别(P<0.05)。结论:加强藏族中、青年人群的心脏病和高血压的检查,积极鼓励进行健康检查和健康教育。降钙素基因相关肽和胰岛素样生长因子Ⅱ水平在不同海拔的藏族中、青年中的变化反映了生活在高原地区人群机体具有一定的自我保护反应。
Objective： To determine the prevalence of heart disease and hypertension in young and middle --aged Tibetans at different altitude and the relationship between hypertension and calcitonin gene--related peptide （CGRP） and insulin--like growth factor Ⅱ （IGF--Ⅱ ）. Methods： Young and middle--aged Tibetans from different altitude were recruited and determined the heart disease and hypertension by epidemi- ological method. Level of CGRP and IGF-Ⅱ was measured by radioimmunoassay. Results： There was a difference of episode on heart disease, hypertension, level of CGRP and IGF-Ⅱ among different altitude （P〈0.05）. Prevalence rates of heart disease and hypertension were 10. 01 percent and 13. 97 percent respectively and they were higher in men than in women. Conelusions. The changes on levels of CGRP and IGF-Ⅱ in young and middle--aged Tibetans at different altitude suggest that high altitude nations could have a self--protection response to altitude hypoxia. It is necessary for health examination and education in young and middle--aged Tibetans.
出处
《高原医学杂志》
CAS
2008年第2期17-19,共3页
Journal of High Altitude Medicine
