摘要
综述了磷酰胆碱类功能材料,包括磷酰胆碱有效基团分别在侧链和主链的聚合物,其包含季铵基和磷酸根结构而同时带有正负两种电荷,具有良好的血液相容性和强吸湿特性,对其在生物医学、生物化学以及化妆品领域的应用研究进行了介绍,包括作为抗凝血仿生材料、药用载体材料、基因运载体系材料、生物传感器基材和人造器官等。
This review reflects mainly the research on the phosphatidylcholine analogous polymers, including both side-chain type and main-chain type. The polymers, which have the zwitterionic lipid phosphatidylcholine, possess excellent blood compatibility and high hydrophilicity. Their applications in the fields of biomedicine, biochemistry and cosmetic are discussed, including their usage as non-thrombogenic material, drug delivery nanoparticles, gene cartier, biosensors and artificial organs etc.
出处
《化工进展》
EI
CAS
CSCD
北大核心
2008年第9期1375-1383,共9页
Chemical Industry and Engineering Progress
关键词
磷酰胆碱
功能材料
结构
生化特性
phosphafidylcholine functional materials structure
biochemical characteristic
