期刊文献+

格拉司琼加甲强龙预防肺癌患者含顺铂化疗中胃肠道反应的疗效观察 被引量:1

A strong Qiongjia granisetron in patients with lung cancer-prevention chemotherapy with cisplatin in the gastrointestinal tract effect of reaction
暂未订购
导出
摘要 目的探讨格拉司琼联合甲强龙预防含顺铂化疗所致胃肠道反应的临床效果。方法79例肺癌病人随机分A、B两组,A组病人于化疗第1~5日每日静滴格拉司琼3mg和甲强龙40mg一次。B组病人单用格拉司琼3mg静滴,方法和疗效同A组。结果应用格拉司琼和甲强龙对急性呕吐的有效率达97.7%,对避免呕吐有效率达100%。结论格拉司琼预防肺癌病人含顺铂化疗所致恶心呕吐与与甲强龙有协同作用。 Objective To investigate the joint granisetron prevention with a strong-eisplatin chemotherapy-induced gastrointestinal reactions of clinical effect. Methods 79 cases of lung cancer patients were randomly divided into groups A and B, group A patients in the daily intravenous chemotherapy 1 - 5 granisetron A 3 mg and 40 mg once-strong. Group B patients alone granisetron 3 mg intravenous drip, methods and efficacy of the same group A. Results Granisetren and A-Long acute vomiting efficiency of 97.7 % , in order to avoid vomiting efficiency was 100%. Conclusion: Granisetron prevention of lung cancer patients with eisplatin ehemotherapy-indueed nausea and vomiting and with a strong LONG synergies.
出处 《临床肺科杂志》 2008年第10期1266-1267,共2页 Journal of Clinical Pulmonary Medicine
关键词 格拉司琼 甲强龙 肺癌 化疗 胃肠道反应 granisetren A-Long lung cancer chemotherapy gastrointestinal reactions
  • 相关文献

参考文献8

  • 1张庆.枢丹加地塞米松治疗化疗后急性与迟发性恶心、呕吐观察[J].中国肿瘤临床,1998,25(2):159-160. 被引量:6
  • 2郭锐主编.肿瘤化疗预防及药物治疗.北京:北京医科大学中国协和医科大学联合出版社,1991,712-714.
  • 3Hesketh PL Understanding the pathobiology of chemotherapy induced nausea and vomiting. Proniding a basis for the rapeutic progress. Oncology( Williston Park) ,2004,18 ( 10 Suppl6) :9 - 14.
  • 4Eisenberg P, Mackintosin FR, Ritch P, et al. Efficacy and pharmacokinetics of palonosrtron in patients receiving highty emetogenic cisplatin -based chemotherapy. A dose - ranging clinical study. Ann Oncol, 2004,15 (2) :330 -337.
  • 5Watters J, Riley M, Pedley L, et al. The development of a protocol for the use of 5HT3 antagonists in chemotherapy - induced nausea and vomiting. Clin Oncol( R Coll Radiol) ,2001,13 (6) :422 -426.
  • 6Henzi I, Walder B, Trainer MR. Dexamethasone for the prevention of postoperative nausea and vomiting: a quantitative systematic review. Anesth Anaig,2000,90( 1 ) :186 - 194.
  • 7Tan M. Granisetron:new insights into its use for the treatment of chemotherapy-induced nausea and vomiting. Expert Opin Phamacother, 2003,4(9) :1563 - 1571.
  • 8Chevallier B, Malty M, Paillarse J M, et al. Methyl-Prednisolone anhances the efficacy of ondansetron in acute and delayed cisplatin induced emesis over at least the three cycles. Br J Cancer 1994,70:1170 - 1171.

共引文献6

同被引文献5

引证文献1

二级引证文献2

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部