摘要
目的观察利福昔明片治疗急性细菌感染性腹泻的临床疗效。方法采用随机单盲、平行对照临床试验共48例，其中男37例，女11例。利福昔明组22例（细菌培养阳性8例）；左氧氟沙星组26例（细菌培养阳性9例）。细菌培养总阳性率35．42％（17／48）。结果利福昔明组临床有效率和细菌清除率分别为90．91％（20／22）和87．5％（7／8），左氧氟沙星组为88．46％（23／26）和88．89％（8／9）。结论临床疗效和细菌学疗效显示利福昔明组与左氧氟沙星组相当，疗效肯定。
Objective To assess the efficacy of rifaximin in treatment of acute bacterial diarrhea. Method 48 patients were recruited into the randomized, single blind, parallel-control study （including 37 men and 11 women）. There were 22 cases in rifaximin group, 8 cases were bacterium positive in the group, and 26 cases in levofloxacin group, 9 cases were bacterium positive in the group. The total bacterium positive rate was 35.42% （17/48）. Results For patients of acute bacterial diarrhea, rifaximin bad an effective rate of 90.91% （20/22）, and the bacterial clearance rate was 87.5% （7/8）. Levofloxacin bad the rate of 88.46% （23/26） and 88.89% （8/9）. Conclusions Compared with levofloxacin, rifaximin has the same clinical and bacterialogical efficacy in treatment of acute bacterial diarrhea.
出处
《国际流行病学传染病学杂志》
CAS
2008年第4期239-240,共2页
International Journal of Epidemiology and Infectious Disease
