摘要
为探讨跨声门癌局部扩展及颈淋巴转移的组织病理学特点，将３０例跨声门癌的喉体标本及３５侧颈廓清大体标本行火棉胶包埋，连续切片ＨＥ染色，光镜观察。结果显示：跨声门癌以喉室为中心向声门上区、声门区呈基本均等态式浸润扩展。颈淋巴结转移率为４３．３％（１３／３６）。潜在性转移为３０．０％（６／２０）。将颈淋巴结分为四类，颈部转移淋巴结分为三型、四期。随着颈淋巴结增大，转移率增加，聚融型淋巴结增多，破膜率增加。结论：跨声门癌应定义为以喉室为中心纵向跨区发展的肿瘤。在跨声门癌的局部扩展中，喉室屏障作用较小；跨声门癌应慎行喉部分切除术，行喉手术同时应行肿瘤主体侧颈廓清术。
To study the histopathological characteristics of local invasion and cervical lymph node metastasis in transglottic carcinoma and provide theoretical guide to clinical practice,30 laryngectomy and 35 neck dissection specimens were studied by serial section,HE staining and observation under light microscope.The results showed that transglottic carcinomas originated from the ventricle invaded supraglottic and glottic areas equally. The metastatic rate of cervical lymph nodes was 43.3%; the latent metastatic rate was 30%. The metastatic and extracapsular perforation rates as well as the number of the aggregated fusion lymphnodes increased with the increase in the size of the lymphonodes. It was concluded that the transglottic carcinoma should be defined as one with the main lesion locates in the ventricle, or the ventricle being the center with transglottic spread. Since the barrier of ventricle was weak, partial laryngectomy should be performed with care, and ipsilateral neck dissection shoud be included during operation.
出处
《中华耳鼻咽喉科杂志》
CSCD
1997年第6期329-331,共3页
Chinese Journal of Otorhinolaryngology
关键词
喉肿瘤
淋巴转移
病理学
外科
Laryngeal neoplasms Lymphatic metastasis Pathology, surgical Transglottic cancer
