摘要
目的:探索妇消宁泡腾栓制备的最佳基质处方及质量控制标准。方法:以pH值为指标采用正交试验法对妇消宁泡腾栓的处方进行优化;薄层色谱法对制剂中的青黛、黄柏进行定性鉴别。结果:优化处方以0.43g酒石酸、0.16g碳酸氢钠、2.00g药物混合为最佳用量比,与基质S40制栓。结论:制剂稳定,质量控制方法简便、准确。
Objective：To optimized the formula for the fuxiaoning effervescent suppository and establish its quality control standard. Methods：The formula of the fuxiaoning effervescent suppository was optimized by ortyogonal experiment with pH as index.Indigo Naturalis,Cortex Phellodendri were identified by TLC. Results：The optimized formula was as follows：The used level ratio of tartaric acid,baking soda and medica powder were 0.43,0.16,2.00 g and prepared were S40. Conclusion： The preparation is stationary and the quality control method were convenient and accurate.
出处
《中国医药导报》
CAS
2008年第24期42-43,共2页
China Medical Herald
关键词
妇消宁泡腾栓
正交试验
质量控制
PH
薄层层析法
Fuxiaoning effervescent suppository
Ortyogonal experiment
TLC
pH
Quality control
