摘要
目的:评价主动免疫联合HCG治疗原因不明反复自发性流产的临床疗效,为临床原因不明习惯性流产的治疗寻求最佳方案。方法:385例原发性原因不明习惯性流产患者随机分为3组。A组166例,接受主动免疫联合HCG治疗;B组143例,单纯接受主动免疫治疗;C组76例单纯接受HCG治疗;另有74例继发性原因不明反复自发性流产患者,为D组,全部接受主动免疫联合HCG治疗。结果:治疗后A组妊娠成功率为91.25%,B组为72.52%,C组为29.85%,D组为84.62%;A组、B组、C组两两比较差异有显著性(P<0.01);A组与D组比较差异无显著性(P>0.05)。结论:主动免疫联合HCG治疗原因不明习惯性流产疗效显著,值得在临床原因不明习惯性流产治疗中推广应用。
Objective： To evaluate the clinical effect of treatment of patients with unexplained recurrent spontaneous abortion （ UR- SA） by active immunotherapy combined with human chorionic gonadotropin （HCG） and look for a best therapeutic strategy to treat URSA. Methods： 385 cases with primary URSA were randomly divided into three groups： 166 cases （group A） were treated with active immunotherapy combined with HCG, 143 cases （ group B） simply with active immunotherapy and 76 cases （ group C） simply with HCG. 74 cases with secondary URSA （group D） were treated with active immunotherapy combined with HCG. Results： The rate of successful pregnancy of group A, B, C and D were 91. 25%, 72. 52%, 29. 85% and 84. 62%, respectively. There were significant differences between group A and B （ P 〈 0. 01 ）, A and C （ P 〈 0. 01 ）, B and C （ P 〈 0. 01 ） ; there was no significant difference between group A and D （ P 〉 0. 05） . Conclusion. It is the most effective method of treatment of URSA by active immunotherapy combined with human HCG, which is worth further widespread application in clinical treatment of URSA.
出处
《中国妇幼保健》
CAS
北大核心
2008年第24期3421-3423,共3页
Maternal and Child Health Care of China
关键词
免疫治疗
主动
习惯性流产
HCG
Immunotherapy
Recurrent spontaneous abortion
HCG
