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尿毒症继发性甲状旁腺亢进两种手术方式的疗效比较 被引量:16

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摘要 目的:比较甲状旁腺次全切除与甲状旁腺全切除加自体前臂种植术治疗尿毒症维持性血透患者严重、继发性甲状旁腺功能亢进(SHPT)的临床疗效。方法:对2002年8月~2007年12月期间在我院接受甲状旁腺切除术13例患者资料(甲状旁腺次全切6例,甲状旁腺全切加自体前臂种植7例)进行回顾性分析,包括定位诊断,以及手术前后完整甲状旁腺激素(iPTH)、血钙、血磷、钙磷乘积、红细胞比容(Hct)进行比较。结果:术前分别行B超和颈部放射性核素显像断层扫描(ECT)的6例患者,B超对肿大甲状旁腺的检出率明显高于ECT。两组患者组内iPTH术后(3d,1周,1月,3月)较术前有明显的下降,有统计学意义;术后血钙、血磷及其乘积较术前明显下降,有统计学意义;术后Hct与术前水平接近,无统计学意义。两组间术前、术后iPTH及血钙、血磷、钙磷乘积水平接近,无统计学意义。结论:在两种术式均能有效的治疗SHPT和均有复发可能的情况下,甲状旁腺全切除加自体前臂种植术的二次手术简单易行,有一定的选择优势。
出处 《中国中西医结合肾病杂志》 2008年第8期710-712,共3页 Chinese Journal of Integrated Traditional and Western Nephrology
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参考文献6

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