摘要
目的观察健康促进手段对膀胱癌术后患者肿瘤复发、生活质量及自我感受评价的影响。方法选取2002年3月至2005年3月我院104例浅表性膀胱癌术后患者随机分为两组，一组单独使用卡介苗（单独BEG组）膀胱灌注治疗，另一组使用卡介苗（BEG）膀胱灌注治疗同时行健康促进手段（BEG＋健康促进组），观察其肿瘤复发、生活质量及自我感受评价。结果所有病例随访7．3～36．0个月，平均28．5个月。单独BEG组复发17（17／51）例，0—12个月、13—24个月、25—36个月分别为2．6、9例，第1年复发率为3．9％，第2年复发率为11．8％，第3年复发率为17．6％；BEG＋健康促进组复发11（11／53）例，0—12个月、13—24个月、25～36个月分别为2、7、2例，第1年复发率为3．8％，第2年复发率为13．2％，第3年复发率为3．8％，第1、第2年两组复发率差异无统计学意义（均P〉0．05），第3年两组复发率差异有统计学意义（X^2=5．29，P〈0．05）。两组首次膀胱癌术后出院时症状自评量表（SCL-90）自我感受评分和生活质量评分比较，差异无统计学意义（P〉0．05），随诊满3年进行生活质量及自我感受评价，BEG＋健康促进组生活质量明显改善（X^2=6．47，P〈0．05），自我感受评价负面情绪明显减少（P〈0．01）。结论对膀胱癌术后患者使用健康促进手段可显著降低其远期肿瘤复发率，并能明显改善患者的生活质量及自我感受。
Objective To observe the effects of health promotion on tumor recurrence, quality of life and self feeling evaluation of patients with superficial bladder carcinoma. Methods 104 patients with superficial bladder carcinoma treated in our hospital from March 2002 to March 2005 were divided to two groups randomly. The patients in one group were treated by bladder irrigation with Bacille Calmette Guerin （BCG） simply, and those in the other group were treated by bladder irrigation and health promotion. Tumor recurrence, quality of life and self feeling evaluation between the two groups were compared. Results All patients were followed up for 7.3 - 36.0 months （ mean 28.5 months）. 17 patients （ 15/51 ） in the simple BCG irrigation group had tumor recurrence in 0 -12 months （2 patients）, 13 -24 months （6） and 25 - 36months（9） respectively. The recurrence rate in the first year was 3.9% , in the second year 11.8% and in the third year 17.6%. Eleven （11/53） patients had in the BCG irrigation and health promotion group, in 0- 12 months（2）, 13 -24 months（7） ,and 25 -36 months（2） respectively. The recurrence rate in the first year was 3.8% , in the second year 13.2%, and in the third year 3.8%. There were no significant differences in the recurrence rates of the first and second year between the two groups （ P 〉 0.05 ）, but there was significant difference in the recurrence rate of the third year between the two group （ X^2 = 5.29, P 〈 0.05）. There were no significant differences in self feeling SCL-90 evaluation and quality evaluation of life after the first discharging between the two groups （ P 〉 0.05）. After 3-year follow up, the life quality of the patients in the BCG irrigation and health promotion group was improved obviously compared with the simple BCG group （X^2 = 6.47 ,P 〈0.05） , and the bad negative emotion was diminished obviously compared with the simple BCG group （ P 〈 0.05 ）. Conclusion Health promotion after operation on the patients with superficial bladder carcinoma can decrease the long-term tumor recurrence rate obviously, and improve the quality of life and self feeling significantly.
出处
《中华健康管理学杂志》
CAS
2008年第4期210-212,共3页
Chinese Journal of Health Management
关键词
膀胱肿瘤
肿瘤复发
健康促进
Bladder cancer
Recurrence
Health promotion
