摘要
目的观察适形放疗联合化疗治疗局部晚期胰腺癌的疗效。方法将2003-2006年收治的52例局部晚期胰腺癌患者,其中男性39例,女性13例,年龄46~75岁,中位年龄52岁,依照1989年UICC标准分期,Ⅱ期18例,Ⅲ期34例;胰头癌31例,胰体尾癌21例。所有病例均经放射治疗和化疗。采用SPSS10.0统计软件进行统计分析。结果全组35例1年内死亡,其中10例6个月内死亡,17例生存期超过1年,中位生存期12.25个月。结论三维适形放疗结合化疗为不能手术的胰腺癌患者提供了有效的综合治疗方法,可有效控制肿瘤,解除梗阻,消退黄疸,患者一般状况快速改善,明显提高了患者生存质量和生存期。
Objective To evaluate the curative effect of conformal radiotherapy combined chemotherapy for local advanced pancreatic cancer. Methods From 2003 to 2006,52 patients with local advanced pancreatic cancer were enrolled in this experiment. There were 39 male and 13 female patients, with a median age of 52 years (ranged,46-75 years). According to UICC classification of pancreatic carcinoma, 18 patients were identified as stage Ⅱ,34 patients were identified as stage Ⅲ. 31 patients had pancreatic head carcinoma,21 patients had pancreatic body and tail carcinoma. All patients were treated with radiotherapy com- bined chemotherapy. Statistical analyses were done with SPSS version 10.0. Results 35 patients died within 1 year of which 10 cases died within 6 months. 17 patients survived more than 1 year. The median survival time was 12.25 months. Conclusions The conformal radiotherapy combined with chemotherapy is an effective method for inoperative pancreatic cancer.
出处
《中华全科医学》
2008年第9期927-928,共2页
Chinese Journal of General Practice
关键词
局部晚期胰腺肿瘤
适形放疗
化疗
Local advanced pancreatic cancer
Conformal radiotherapy
Chemotherapy