摘要
目的探讨老年高血压病患者动态脉压与颈动脉粥样硬化斑块、血清胆红素的关系。方法将120例老年原发性高血压病患者按照脉压的不同,分为3组:PP1组(脉压<51mmHg,1mmHg=0.133kPa),PP2组(脉压51～65mmHg),PP3组(脉压>65mmHg),分别测定颈动脉粥样硬化斑块程度、血清胆红素水平。结果随着脉压增高,颈动脉粥样硬化斑块程度越严重,PP3>PP2>PP1(P<0.05);血清胆红素水平越低,PP3<PP2<PP1(P<0.05)。结论颈动脉粥样硬化、血清胆红素水平与脉压高低密切相关,适当提高血清胆红素水平可能防止动脉粥样硬化进展,降低脉压,减轻高血压靶器官损害。
Objective To investigate the relationship between ambulatory pulse pressure, carotid atherosclerosis and serum bilirubin in aged patients with essential hypertension. Methods 120 elderly essential hypertensive patients were divided into 3 groups according to the grade of pulse pressure, PP1 group（pulse pressure 〈 51 mm Hg）, PP2 group（51 mm Hg ≤pulse pressure ≤65 mm Hg） , PP3 group（ pulse pressure 〉 65 mm Hg）. The grade of atheroma and serum bilirubin concentration were examined at the same time. Results The difference of carotid atheroma was significant （ P 〈 0.05 ） , PP3 〉 PP2 〉 PP1 ; the difference of serum bilirubin concentrations was also significant （ P 〈 0.05 ）, PP3 〈 PP2 〈 PP1. Conclusions In 120 elderly essential hypertensive patients, carotid athersclerosis and serum bilirubin were correlated with the pulse pressure. It might be concluded that higher serum bilirubin could prevent the progression of atheroselerosis, decrease pulse pressure, relieve the organ damage induced by hypertension.
出处
《中华全科医学》
2008年第9期892-893,共2页
Chinese Journal of General Practice
关键词
老年
高血压
脉压
动脉粥样硬化
胆红素
Aged
Hypertension
Pulse pressure
Carotid atherosclerosis
Serum bilirubin
