摘要
目的:探讨SSBP2 mRNA在初发急性非淋巴细胞白血病中的表达。方法:利用半定量RT-PCR检测64例初发急性非淋巴细胞白血病患者及20例正常对照SSBP2 mRNA表达,以β-actin作为内参照。结果:64例初发ANLL患者及20例正常对照均表达SSBP2。与正常对照比较,初发ANLL患者SSBP2mRNA表达水平为(0.410±0.216)与对照组(0.383±0.172)差异无显著性(P>0.05)。结论:初发ANLL中SSBP2mRNA表达无异常改变,SSBP2表达可能并不参与急性非淋巴细胞白血病的发生。
Objective：To explore SSBP2 mRNA level in primary acute myeloid leukemia patients. Methods：Reverse transcription Polymerase chain reaction（RT-PCR） was used to assay the expression level of SSBP2 mRNA in 64 cases of primary acute myeloid leukemia（ANLL）and 20 normal cases ,β-actin was used as contral gene. Results ：SSBP2 was normally expressed in 64 cases of primary ANLL and 20 normal cases. The SSBP2 mRNA level in primary ANLL （0. 410±0. 216） was no statistically significant difference compared with in normal cases（0. 383±0. 172）（P〉0.05）. Conclusions：Expression of SSBP2 mRNAwas not changed in the primary ANLL patients ,expression of SSBP2 may be not involved in the development of ANLL.
出处
《临床医药实践》
2008年第6期403-404,共2页
Proceeding of Clinical Medicine
