摘要
合成了14个N-酰化苄基四氢异喹啉化合物,并选择其中10个化合物做了抗血小板聚集作用的体外试验,结果发现多数均具有一定的活性,为今后该类化合物的研究提供了参考数据。
Fourteen N acylated tetrahydrobenzylisoquinoline derivatives were designed and synthesized of which 13 were not reported previously. The preliminary pharmacological tests showed that most compounds exhibited various degrees of antiplatelet aggregation in vitro .
出处
《中国药科大学学报》
CAS
CSCD
北大核心
1997年第5期255-259,共5页
Journal of China Pharmaceutical University
关键词
N-酰化四氢异喹啉
抗血小板聚集
合成
N Acyltetrahydroisoquinoline
Antiplatelet aggregation
Synthesis