摘要
本文观察我院1988～1995年收治肝硬化并发食管静脉曲张破裂出血（EVB）以呕吐鲜血为首发症状者106例121次。通过统计分析发现EVB的发生冬季较夏季（P＜0．01）、春季较夏季（P＜0．05）显著增多，24小时EVB的发生6.36Am及8.36pm有两次高峰。提示肝硬化EVB的发生有明显的昼夜节律和季节周期性变化。
To study the relationship between the time and the occurence of esophageal variceal bleeding (EVB) in patients with liver cirrhosis, the precise moment of onset of EVB was observed in 121 episodes of 106 patients with liver cirrhosis, and the origin of bleeding was confirmed by emergency endoscopy in this study. statistical analyses were made with chi-square test and circular distribution. The constituent ratios of EVB in spring, Summer, autumn and winter were 28.1%, 14.05%,23.5% and 34.7% respectively, much more patients with EVB in winter and spring than in summer (P<0. 05). January 12 was the peak in EVB occnrence during a year (P<0. 05). In addition, there were two peaks in the occurence of EVB during a 24hr period which were 8:36PM (P<0. 05) and 6:36AM (P<0. 05). There were significant circadian rhythms in the occurence of EVB. These findings may be important to deermine the optimum time of drug administering against the occurence of EVB in patients at high risk.
出处
《泸州医学院学报》
1997年第2期140-142,共3页
Journal of Luzhou Medical College
