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提高脑神经磁刺激感应电场聚焦性能的线圈参数优化方法的研究 被引量:7

Optimization of the Coil Focalizing the Electrical Field Induced by Magnetic Stimulation in the Human Brain
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摘要 本研究提出一个衡量磁刺激线圈聚焦性的比较系数,比较不同形状线圈的感应电场聚焦性,研究线圈参数的优化方法。我们建立了磁刺激感应电场分布的数学模型,以Matlab作为仿真工具,以能够反映线圈刺激效果的比较系数ξ为指标,分析比较了几种不同线圈的聚焦性,以及成不同角度的线圈聚焦性。结果表明:四叶玫瑰形为刺激聚焦性最好的线圈形状,该线圈半径越小,聚焦性越好,成102°角的四叶玫瑰线形线圈具有最佳聚焦性,而且112°角四叶玫瑰形线圈与89°角线圈组合成的线圈阵列聚焦性最好。由此说明本研究中的比较系数可用于比较线圈聚焦性,对线圈参数的优化设计具有一定的指导意义。 A coefficient to evaluate the focus of the electrical field intensity induced by magnetic stimulation was firstly presented in this study, which was used as an index of focus.Matlab was used as the tool to simulate the distribution of induced electrical field, mathematic model was set up to study the distribution of the electric field induced by magnetic stimulation, comparison was made to analyze the focus of coils with different shapes. Result showed that the four-leaf rose shape coil was the best one compared with other five different shapes of coil. As a result of optimizing other parameters of the coil, the smaller radius of the coil was the better choice and the angle between four-leaf rose coil of 102° was better than that of other values. Furthermore, when the four-leaf coil with angle of 112° assembled with a coil of 89°, the more focused electrical field was obtained.These results demonstrate that the coefficient proposed can be used to study the focus of electrical field induced by magnetic stimulation, it may be a guideline to the optimization of the coil's parameters.
出处 《生物医学工程研究》 2008年第2期74-78,共5页 Journal Of Biomedical Engineering Research
基金 天津市重点攻关项目(06YFSZSF00700) 科技部科学仪器设备升级改造专项项目(2006JG004700)
关键词 磁刺激 线圈 聚焦性 感应电场 比较系数 四叶玫瑰线形 Magnetic stimulating,Coil,Focus,Induced electrical field,Comparing coefficient,Four-leaf rose shape
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参考文献9

  • 1[1]George MS,Wassernlanla EN.Rapid-rate transcrania1 magnetic stimulation l(rTMS) and ECT[J].Convulsive Ther,1994,10:251-3.
  • 2[2]Martin JL,Barbanoj MJ,Schlaepfer TE,et al.Repetitive transcranial magnetic stimulation for the treatment of depression[J].Br J Psychiatry,2003,182:480-491.
  • 3[3]Hoppner,Schulz M,Irmisch G.Antidepressant efficacy of two different rTMS procedures:high frequency over left versus low frequency over right prefrontal cortex compared with stimulation[J].Eur Arch Psychiatry Clin Neurosci,2003,253:103-109.
  • 4[4]Eschweiler GW,Wegerer C,Schlotter W,et al.Left prefrontal activation predicts therapeutic effects of repetitive transcranial magnetic stimulation (rTMS) in major depression[J].Psychiatry Res,2000,99:161-72.
  • 5王修信 ,胡维平 ,杨永栩 ,梁冬冬 ,周建玲 ,卢小春 .磁刺激中深度感应电场分布的计算[J].中国医学物理学杂志,2005,22(5):660-662. 被引量:1
  • 6殷涛,刘志朋.脑磁刺激空间感应电场分布的数学模型与计算机仿真[J].中国生物医学工程学报,2004,23(6):529-536. 被引量:5
  • 7[7]Ren CY,Tarjan PP,Popovic DB.A novel electric design for electromagnetic stimulation -the slinky coil[J].IEEE Transactions on Biomedical Engineering,1995,42(9):918-925.
  • 8[8]Padberg F,Flavia di Michele,Zwanzger P,et al.Plasma concentrations of neuroactive steroids before and after repetitive transcranial magnetic stimulation (rTMS) in major depression[J].Neuropsychopharmacology,2002,27(5):874-878.
  • 9[9]Couturier J L.Efficacy of rapid-rate repetitive transcranial magnetic stimulation in the treatment of depression:a systematic review and meta-analysis[J].Rev Psychiatry Neurosci,2005,30(2):83-90.

二级参考文献12

  • 1王修信,胡维平,杨永栩,梁冬冬.磁刺激中线圈感应电场的聚焦性研究[J].北京生物医学工程,2005,24(1):33-35. 被引量:6
  • 2Rueter C,Battocletti JH, Myklebust J. Magnetic stimulation in peripheral nerves[C]. IEEE Engineering in Medicine and Biology Society 10th Annual Int.Conf.IEEE,New York,1988,928-929
  • 3Cohen LG,Bradley J,Roth JN,et al. Effects of coil design on delivery of focal magnetic stimulation technical considerations[J].Electroencephalography and Clinical Neurophsiology,1990,75:350-357.
  • 4Roth BJ,Saypol JM, Hallett M.A theoretical calculation of the electric field induced in the cortex during magnetic stimulation[J].Electroencephalography and Clinical Neurophysiology, 1991, 81:46-56.
  • 5Ueno S, Tashiro T,Harada K,etal. Localized stimulation of the human brain and spinal cord by a pair of opposing pulsed magnetic fields[J]J. Appl. Phys,1990,66:5838-5840.
  • 6Ueno S, Tashiro T, Harada K,et al. Neural tissues in the brain by means of paired configuration of time-varying magnetic fields[J]. J. Appl. Phys,1988,64:5862-5864.
  • 7Ren CY, Tarjan PP, Popovic DB.A novel electric design for electromagnetic stimulation-the slinky coil[J]. IEEE Transactions On Biomedical Engineering,1995,42(9):918-925.
  • 8Roth BJ,Saypol JM, Hallett M.A theoretical calculation of the electric field induced in the cortex during magnetic stimulation[J]. Electroencephalography and Clinical Neurophysiology, 1991,81:46-56.
  • 9Rusinko JB,Sepulveda NG,Walker CF.Three-dimensional numerical solution of field distribution[C].In:Pro.37th Annual Conf. on Engineering in Medicine and Biology Alliance for Engineering in Medicine and Biology,Washington,Dc,1984.
  • 10Loo C K, Taylor J L, Gandevia S C, et al. Transcranial magnetic stimulation (TMS) in controlled treatment studie[J]. Biol Psychi atry, 2000,47:325-331

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