摘要
利用超声强化[emim]Br(溴化1-乙基-3-甲基咪唑)-水体系从黄花蒿粉末中提取青蒿素.正交实验和单因素实验结果表明,影响黄花蒿中青蒿素提取因素的显著性次序为液固比>提取时间>提取温度>超声波功率>占空比.综合考虑单因素实验结果及成本,得出优化工艺条件为黄花蒿原料粒度0.38mm,液固比50mL/g,提取时间30min,提取温度20℃,超声波功率600W,占空比1.6s/0.4s.在上述条件下青蒿素提取量为4.37mg/g,提取率为97%.
Extraction of artemisinin from Artemisia annual L. using ionic liquid [emim]Br （1-ethyl-3-methylimidazolium bromide）water system enhanced by ultrasonic wave was investigated. Through orthogonal and single factor experiments, the results showed that the sequence of notability of artemisinin extraction factors was： liquid-to-solid ratio 〉 extraction time 〉 extraction temperature 〉 ultrasonic wave power 〉 duty ratio. Comprehensively considering single factor experiments and production cost, the optimum extraction conditions were obtained as Artemisia annual L. granularity at 0.38 mm, liquid-to-solid ratio 50 mL/g, extraction time 30 min, extraction temperature 20℃, ultrasonic wave power 600 W and duty ratio 1.6 s/0.4 s. Under the above conditions, the extraction amount of artemisinin was 4.37 mg/g and the extraction rate 97%.
出处
《过程工程学报》
CAS
CSCD
北大核心
2008年第4期774-778,共5页
The Chinese Journal of Process Engineering
基金
国家高技术研究发展计划(863)基金资助项目(编号:2007AA021501)
关键词
青蒿素
黄花蒿
溴化1-乙基-3-甲基咪唑
超声强化提取
artemisinin
Artemisia annual L.
1-ethyl-3-methylimidazolium bromide
ultrasonic wave enhanced extraction
