摘要
为探讨血清孕酮（P）及hCG水平对异位妊娠药物治疗结果的影响，对48例未破裂型异位妊娠药物治疗前血清P及hCG水平进行了放射免疫测定，并以hCG日增倍数（hCG1／DT）反映hCG增长率。结果：治疗成功组血清P水平及hCG1／DT明显低于失败组。P≤30nmol／L者治疗成功率明显高于P＞30nmol／L者，以P≤30nmol／L预测治疗结果的敏感性及特异性分别为73．1％及81．8％，阳性及阴性预测率分别为82．6％及72％。结论：血清P水平是影响治疗结果的重要因素，且为预测治疗结果的有效指标。
To study the effect of the serum levels of progesterone (P) and hCG on themethotrexate (MTX) treatment outcome of ectopic pregnancy, the serum levels of P and hCG weredetermined in 48 cases of unruptured ectopic pregnancy by radioimmunassay before MTX adminstration. The results showed that the levels of P arid hCG 1/DT values were significantly lower inthe resolved group than that in the unresolved group. The rate of resolution in the group with P≤30nmol/L was higher than that in the group with P>30nmol/L. P≤30nmol/L was chosen as predictive threshold for treatment outcome, with sensitivity of 73.1%, specificity of 81.8 %, positivepredictive value of 82.6% and negative predictive value of 72%. The results suggest that theserum level of P is a mainly factor to affect the medical treatment outcome of ectopic pregnacy,and is an effective mark to predict the outcome.
出处
《北京医学》
CAS
北大核心
1997年第6期345-347,共3页
Beijing Medical Journal
关键词
异位妊娠
药物疗法
血清
孕酮
HCG
Pregnancy,ectopic Progesterone Chorionic gonadotropinTreatment,Medical
