摘要
报告15例回纹型风湿病患者。其临床特征为反复发作的四肢关节肿痛，多于数小时或数天内自行缓解。发作间歇期介于2周至1年不等，间歇期内无症状或异常体征。本组患者中受侵的关节依次为掌指关节（86．3％）、近端指间关节（80．0％）、腕关节（66．7％）、膝关节（53．3％）、肘关节（40．0％）、踝关节（13．3％）和跖趾关节（2．0％）。在关节炎发作时，1例伴有低热，3例关节周围出现结节，1例有关节腔内积液。出现关节肿痛时血沉、C反应蛋白、类风湿因子和X线双手关节相都无明显异常。4例患者在临床晚期时出现类风湿关节炎的临床表现和血沉增快，2例类风湿因子转为阳性，1例的X线关节相和另1例的MRI检查出现骨侵蚀证象。这4例病灶演变过程支持回纹型风湿病可能工类风湿关节炎的一种特殊类型。
Palindromic rheumatism (PR) is an uncommon disease. We reported 15 patientswith typical clinical manifestation of this disorder, which was characterized by recurrent episodesof acute arthritis with periarticular inflammation. Each attack of arthritis usually lasted from a fewhours to several days before disappearing completely with no residual articular effect. The affectedjoints included palms, soles, knees and ankles with redness and swelling. Except one patient withlow fever, the other 14 patients were lack of constitutional symptoms and laboratory abnormalitiesduring their episodes of acute arthritis. Among 15 patients, there were 3 patients associated withperiarticular nodule and 1 patient with synovial fluid. At the later stage of the course there were 4patients, whose attacks of arthritis were progressively worsened both in frequency and in intensity, developing the clinical manifestations of rheumatoid arthritis (RA) including the abnormality oferythrocyte sedimentation rate (ESR) in 4 patients, seropositivity of rheumatoid factor in 2 patients, and X-ray bone erosion in one case and MRI abnormality in another case. From the linksbetween the PR and RA we considered that PR may be a specific spectrum of RA.
出处
《北京医学》
CAS
北大核心
1997年第6期338-341,共4页
Beijing Medical Journal
