摘要
采用２０１ＴｌＧＩＫ溶液（２０１铊葡萄糖胰岛素氯化钾）心肌灌注显像，对２８例陈旧性心肌梗塞患者的梗塞区域心肌的存活性进行研究。输注ＧＩＫ溶液后再次心肌断层显像，结果：在２８例陈旧性心肌梗塞患者的１１９个梗塞节段中有４５个节段（３７．８％）有存活心肌。１５例做经皮冠状动脉内气囊扩张术或冠状动脉搭桥术的患者，术前７６个梗塞节段中有２８个节段于输注ＧＩＫ溶液后显像证明有存活心肌（３６．８％）；术后复查静态２０１Ｔｌ心肌断层显像有３２个节段存活（４２％），两者间符合率为８７．５％（２８／３２）。本研究证明在陈旧性心肌梗塞区内仍有存活心肌存在。
To observe myocardial viability in infarcted area in patients with older myocardial infarction, we perfomed pilot study to identify the severely ischemic myocardium using the infusion of a thalliumglucoseinsulinpotassium solution.Results were compared with those obtained in rest images. In 336 segments of 28 patients 201Tl rest images,45 out of 119 infarction segments, revealed 201Tl activity after GIK infusion 37.8%. In 180 segments of 15 patients with PTCA or CABG , 28 out of the 76 infarction segments revealed 201Tl activity after GIK infusion 36.8%.42% segments with rest images were detected after operation.These results confirm that continuous infusion of 201Tl with a low dose of insulin in a glucose and potassium chloride solution is safe and may enhance cellular uptake of the radiotracer in severely ischemic regions especially in older myocardial infarction.This study suggests that within the old infarcted area, there still exists viable myocardium.
出处
《首都医科大学学报》
CAS
1997年第4期327-329,共3页
Journal of Capital Medical University
关键词
心肌梗塞
存活心肌
^201Tl-GIK
心肌显像
older myocardial infarction
viable myocardium
201ThalliumGIK
myocardial scintigraphy
