摘要
对有无雷诺氏现象的系统性红斑狼疮患者的血小板指数、血浆丙二醛及谷胱甘肽过氧化物酶水平进行了比较分析。与无雷诺氏现象患者比较,有雷诺氏现象的患者平均血小板体积、血小板体积分布宽度及丙二醛水平增高(P<0.05,P<0.01,P<0.01),而谷胱甘肽过氧化物酶活性降低(P<0.05),说明血小板及脂质过氧化反应异常在雷诺氏现象发生中发挥了重要作用。
The platelet indexes, plasma malondialdehyde (MDA) content and glutathione-peroxidase(GSH-PX) activity in systemic lupus erythematosus(SLE) patients with and without Raynaud's phenomenon (RP) were analysed. Compared with patients without RP,the levels of mean platelet volume(MPV) > platelet distribution width(PDW) and MDA were higher(P<0. 05,P<0. 05,P<0. 01) while the activity of GSH-PX was lower(P<0. 05) in RP group,which suggested that abnormality of platelet and lipid-peroxidation may play an important role in the pathogenesis of RP.
出处
《天津医药》
CAS
1997年第12期714-716,共3页
Tianjin Medical Journal
