摘要
为了掌握南宁市新生儿腹泻的特点，有效控制新生儿腹泻，我们于１９８８年３月至１９９３年２月对南宁市内五家医院７８７例新生儿腹泻粪便进行了病原检测，耐药性监测和流行病学分析。检出各种致泻病原体２６１例，总检出率３３．２％。计２４种病原，细菌性感染占９６．６％。社会获得性腹泻检出率为２７．５％，病原性大肠菌占７１．３％，以ＥＰＥＣ为主（８８／１６０）。医院内获得性腹泻检出率４９．０％，以沙门氏菌为主（４５．５％），呈爆发流行；次为ＥＰＥＣ、绿脓杆菌、变形杆菌，呈散发性。根据院内流行发生的主要原因，采取可行性有效措施，院内获得性腹泻发生率由２２．７％降至２．７％，近四年，未超过２．０％。新生儿主要致病菌对最常用的氨苄青霉素、硫酸卡那霉素及庆大霉素的耐药率很高（７６．９～１００．０％）。
787 stool specimens of neonatal diarrhea from 5 hospitals of Nanning city are tested for etiological examination,drug resistance surveillance and epidemiolgical analysis to understand characterisitic of neonatal diarrhea and control effectively neonatal diarrhea from March 1988 to February 199324 kinds of lapactic pathogens were detected in 261 stool specimens.Total detectable rate was 332% and bacterial infection accounted for 966%.Detectable rate of social acquired diarrhea was 275%Pathogenicity Bacius coli accounted for 713%Most of stains were EPEC(88/160).Dectectable rate of hospital acquired diarrhea was 490%.Most of stains were salmonella.It was furmanant epidemic. EPEC, pseudomonas aeruginosa,bacillus proteus were following. They were sporadic. In accordance with principal reasons of epidemic and genesis,we applied feasible and effective control measures and incidence of neonatal diarrhea decreased from 227% to 27% for 4 years,the incidence was no higher than 20%The drug resistant rate of pathogen was high to common antibiotics such as ampicillin,kanamycin sulfate and gentamicin(769%—1000%). At present,Amikacin is the most ideal antibiotic against neonatal diarrhea caused by bacterial infection
出处
《广西医学》
CAS
1997年第6期935-940,共6页
Guangxi Medical Journal
基金
广西区卫生厅资助
关键词
新生儿
腹泻
病原检测
防治
南宁市
nenatal diarrhea
etiological examination
hospital infection
antibiotic
