摘要
目的:评价在应用低分子肝素和阿司匹林的基础上,使用GPⅡb/Ⅲa受体拮抗剂国产替罗非班治疗急性冠状动脉综合征的疗效。方法:选取60例急性非ST段抬高心肌梗死和不稳定性心绞痛患者。按就诊顺序分为受试组和对照组各30例。结果:病人应用国产替罗非班(欣维宁)3天后的心绞痛观察结果比较,P=0.273,差别没有统计意义,可认为应用国产替罗非班(欣维宁)3天后对照组和受试组疗效相差不大。病人应用国产替罗非班(欣维宁)10天后的心绞痛观察结果比较,P= 0.038,差别具有统计意义,可认为应用国产替罗非班(欣维宁)10天后受试组疗效明显好于对照组。结论:国产替罗非班(欣维宁)在急性冠脉综合征常规治疗基础上可以进一步缓解急性冠脉综合征的心绞痛症状。
Objective：Assess the offects of GPⅡb/Ⅲa receptor - inhibitor, Home - produced, tirofiban, on treatment ACS on the basis of using heparin and aspirin. Methods： 60 cases with Acute myocardial infarction and unstable angina were selected. The cases are divided into testing group and control group, testing group 30 cases, control group 30 cases. Results： within 3days, difference between testing group and control group in clnical symptoms is not significant statistically （Χ^2= 1. 200, P = 0. 273, P 〉 0.05 ） ; 10days after treatment, the difference is significant statistiscally （Χ^2 = 4. 310, P = 0. 038, P 〈 0. 05 ）, which shows the effects in testing group obviously are better than those in control group. Conclusion： Home - produced tirofiban can relieve clinical symptoms of patients with ACS such as chest depression and chest pain.
出处
《中国医药导刊》
2008年第4期562-563,共2页
Chinese Journal of Medicinal Guide
关键词
国产替罗非班
急性冠脉综合征
Home- produced Tirofiban
Acute coronary syndrome
