摘要
目的观察长托宁与阿托品治疗急性有机磷农药中毒的临床效果。方法156例急性有机磷农药中毒的患者随机分为A、B、C三组,A组给予长托宁治疗,B组给予长托宁+阿托品治疗,C组给予阿托品治疗,各组配合给予氯解磷定解毒。结果B组与A、C两组比较,在中毒症状消失时间、阿托品化时间、ChE恢复时间、平均住院天数上均有显著性差异。不良反应较C组明显减少,治愈率高。结论长托宁+阿托品救治急性有机磷农药中毒起效快、用量小、副作用少、疗效高、安全可靠。
Objective To observe the effects of long-acting tuoning（penehyclidine hydrochloride） and atropine in the treatment of acute organophosphorus pesticide poisoning（AOPP）. Methods 156 cases with oral AOPP were randomly divided into group A,B and C. Patients in group A were treated with long-acting tanning and pralidoxime chloride. Patients in group B were treated with atropine and long-acting Tuoning,which combined with pralidoxime chloride. Patients in group C were treated with atropine and pralidoxime chloride. Results Compared group B（ Long-acting Tanning and Atropine） with group A and B, There were significant differences in disappearance time of poisoning symptoms,atropinization time,recovery time of chohnesterase and average hospitalization duration. Compared to group C, there were lower incidence of side reactions and higher curing rate in group B. Conclusion Penehyclidine Hydrochloride and atropine in the treatment of acute organophosphorus pesticide poisoning were effect quickly, the amount of small,less side effects, high efficacy, safe and reliable.
出处
《中国现代医生》
2008年第21期39-40,43,共3页
China Modern Doctor
关键词
急性有机磷农药中毒
长托宁
阿托品
Acute organophosphorus pesticide poisoning
Penehyclidine hydrochloride
Atropine
