摘要
目的:研究乌贼墨的体外抗菌作用和对小鼠感染模型的体内抗感染作用。方法:琼脂打孔法检测乌贼墨体外抗菌活性,并通过小鼠死亡率观察乌贼墨对小鼠抗感染能力的影响。结果:新鲜乌贼墨与粗提乌贼墨在体外对琼脂打孔法中的金黄色葡萄球菌、大肠埃希菌、肺炎双球菌无抑菌圈产生。但实验组小鼠大肠埃希菌感染后与对照组小鼠比较,其死亡率有明显降低。结论:用琼脂打孔法测新鲜乌贼墨与粗提乌贼墨在体外无抗菌活性,但粗提乌贼墨在体内可以提高小鼠对大肠埃希菌感染的抵抗力。
Objective： To study the effect of antibiosis in vitro and anti-infection in vivo of the squid ink.MethodstThe effect of antibiosis in vitro of the squid ink was detected by agar punch method. The effects of the squid ink on the anti-infection ability of KM mice were measured by the death rate. Results：The strains of Staphylococcus aureus,Escherichia coli, Pneumoniae diplococcus could not be inhibited by the fresh squid ink and abstracted squid ink in vitro by agar punch method. The death rate of KM mouse of EG was lower than CG. Conclusion： The fresh squid ink and abstracted squid ink have no effect of antibiosis in vitro by agar punch method, but the abstracted squid ink can raise the resistibility to E. coli infection of KM mouse.
出处
《中国医药导报》
CAS
2008年第22期31-32,共2页
China Medical Herald
关键词
乌贼墨
免疫作用
抗感染
Squid ink
Immunifaction
Anti-infection
