摘要
目的探讨血液灌流吸附剂对百草枯的吸附作用。方法采用0.5%百草枯溶液200ml、100ml、50ml及0.01%百草枯溶液200ml进行体外循环吸附2h,观察百草枯浓度的变化,以计算活性炭及大孔吸附树脂对百草枯的吸附率。结果百草枯的浓度为0.5%,循环容积为200ml,百草枯含量为1000mg时,活性炭和树脂的吸附率为46%、35%;百草枯的浓度为0.5%,循环容积为100ml,百草枯含量为500mg时,活性炭和树脂的吸附率为65%、47%;百草枯的浓度为0.5%,循环容积为50ml,百草枯含量为250mg时活性炭和树脂的吸附率为88%、57%;百草枯的浓度为0.01%,循环容积为200ml,百草枯含量为20mg时,活性炭和树脂的吸附率为95%、87%。结论在百草枯浓度较低0.01%、较低含量20mg时,活性炭及大孔吸附树脂对百草枯的吸附率无明显差异;在百草枯浓度较高0.5%、较高含量时,活性炭清除百草枯的作用优于大孔吸附树脂;临床上清除百草枯可以根据患者情况选用炭肾或树脂吸附柱进行血液灌流治疗。
Objective To study the adsorption of paraquat by different hemopeffusion adsorbents. Methods We added 0.5% paraquat solution 200 ml, 100ml, 50ml and 0.01% paraquat solution 200 ml in the extracorporeal circulation system for adsorption for 2 hours, observed the change of paraquat concentration, and calculated the adsorption rate of paraquat by activated carbon and macroporous resin. Results when paraquat concentration was 0.5% and the circulation volume was 200ml, the adsorption rate of parquet by activated carbon and resin was 46% and 35%, respectively. With the decrease of circulation volume, the adsorption rate was increased. When the paraquat concentration was 0.01% and the circulation volume was 200ml, the adsorption rate by activated carbon and macroporous resin was 95% and 87%, respectively. Conclusion When the paraquat concentration is lower, the adsorption rate of the activated carbon and macroporous resin is no obvious difference, the removing rate of activated carbon is better than that of macroporous resin when the paraquat concentration is higher, on clinic, doctor can select both Charcoal Kidney or Resin adsorption column to clear paraquat according to the patient＇s situation.
出处
《中国血液净化》
2008年第7期380-382,共3页
Chinese Journal of Blood Purification
