摘要
二乙三胺五乙酸双酐与甘醇单醚反应，得到含多氨基多羧基双酯配体，配体与GdCl36H2O反应生成非离子配合物．配体及配合物用IR、1HNMR和元素分析进行了表征，并测试了配合物的驰豫率，其中3种配合物的弛豫率比已用于临床诊断的Gd（DTPA）强，
Polyaminocarboxylate ligands were synthesized by the reaction of diethylenetriaminepentaacetic dianhydride with glycol monoether, and their Gd(Ⅲ) complexes were also prepared. The structures of the ligands and complexes were confirmed by IR, 1H NMR spectra and elemental anaJysis. The relaxivity of these Gd(Ⅲ) complexes were investigated and the data indicated that three of them showed higher relaxivity as compared to Gd(DTPA).
出处
《波谱学杂志》
CAS
CSCD
北大核心
1997年第4期347-352,共6页
Chinese Journal of Magnetic Resonance
基金
国家"863"高科技项目
