摘要
目的探讨应用无创尿动力学检测早期发现糖尿病性膀胱病（DCP）。方法对70例2型糖尿病患者和30例非糖尿病者进行尿动力学检测，并以糖尿病病程5年为界限将70例患者分为2组，分别应用无创尿动力学方法进行最大尿流率、平均排尿率、初尿意膀胱容量及残尿量测定。结果70例糖尿病患者中膀胱有残余尿者34例，即DCP组，平均残尿量7-139（30．1±27．1）ml，DCP检出率48．6％，无残余尿者36例，即非DCP糖尿病组。正常对照组30例均无残余尿量。与正常对照组相比，DCP组及非DCP糖尿病组最大尿流率、平均尿流率均明显降低（P〈0．01）。糖尿病病程≥5年组最大尿流率、平均尿流率均低于病程〈5年组，但差异无统计学意义（P〉0．05）。结论无创尿动力学检查提示最大尿流率降低和出现膀胱残余尿可作为早期发现和诊断DCP的筛查指标。
Objective To evaluate the early detection of diabetic cystopathy （DCP） with the technology of noninvasive urodynamics. Methods 70 patients with type 2 diabetes mellitus （DM） and 30 normal control subjects were checked with the technology of noninvasive urodynamics. Based on their disease course of less or more than 5 years, the DM patients were divided into two groups. Maximal flow rate, average flow rate, the volume leading to first bladder sensation and residual urine volume were measured by using noninvasive urodynamic technology. Results Among the 70 DM patients, 34 were detected to have bladder residual urine, so the DCP detection rate was 48. 6%. In the patients with DCP, the average residual urine volume was 7 -139 ml （30. 1 ± 27.1 ）ml, while there was no residual urine in the normal control group. As compared with the normal control group, maximal flow rate and average flow rate were decreased in all the patients with DM and those with DCP（ P 〈 0. 01 ）. After follow up of the disease, the patients with a course of more than five years of disease control had even lower maximal flow rate and average flow rate. Conclusion Maximal flow rate decrease and bladder residual urine detected with the technology of noninvasive urodynamics may be widely used in early detection and early diagnosis of DCP.
出处
《中华内科杂志》
CAS
CSCD
北大核心
2008年第7期560-562,共3页
Chinese Journal of Internal Medicine
关键词
糖尿病
膀胱疾病
尿动力学
无创性
Diabetes Mellitus
Urinary bladder diseases
Urodynamics
Noninvasion
