摘要
本文应用放射免疫分析法测定了30例肝硬变患者(16例为失代偿性)血浆心钠素含量及某些临床生化指标。结果表明肝硬变患者早期有效血容量有所增加,心钠素水平升高,而失代偿性肝硬变则有效循环血量明显减少,心钠素水平降低,并存在低蛋白血症。提示在肝硬变早期应予限盐饮食,晚期治疗除适量输入白蛋白外,强调了腹水回输的重要性。
The plasma levels of atrial natriuretic peptide (ANP) and some clinicaltest values were measured by radioimmunoassay in 30 patients with hepatic cirrhosis. The results showed that effective vascular volume andplasma levels of ANP may be increased in patients with compensatedcirrhosis but decreased significantly in patients with decompensated cirrhosis and hypoalbuminemia may also contribute to ascites formation,`The authors suggested that restriction of dietary sodium intake and reinfusion should be taken respectively in compensated and decompensatedcirrhotic patients.
关键词
肝硬变
心钠素
放射免疫法
腹水
atrial natriuretic peptide
hepatic cirrhosis
ascites
radioimmunoassay
