摘要
目的探讨胃肠道间质瘤的临床特点及其诊治方法。方法回顾性分析我院2000年1月-2007年10月收治的胃肠道间质瘤46例的临床资料。结果本组46例均手术治疗。术后随访6月～5年30例，复发7例，转移3例，再次手术7例。全组无手术死亡病例。术后并发胰瘘1例、细菌性腹膜炎1例、切口裂开1例，均治愈。结论外科手术和分子靶向治疗是胃肠道间质瘤的主要治疗手段。对复发和转移者应争取再次手术，同时联合分子靶向治疗。
Objective To study clinical characteristics, diagnosis and treatment of gastrointestinal stromal tumors（GIST）. Methods The clinical data of 46 cases of GIST admitted in our hospital from Jan. 2000 to Oct. 2007 were retrospectively analyzed. Results All 46 patients in this group were treated surgically. During a period of postoperative follow-up of 6 months to 5 years, recurrence occurred in 7 cases, metastasis in 3 cases, re-operation was done in 7 cases. There were no operative deaths. Postoperative complications included pancreatic fistula（ 1 case）, bacterial peritonitis（1 case）, disruption of wound（1 case） ,all of them were cured. Conclusion Surgical operation and molecular targeted therapy are the main means to treat GIST. The patients who recur and have metastasis had better undergo second operation, at the same time molecular targeted therapy was given.
出处
《腹部外科》
2008年第3期167-168,共2页
Journal of Abdominal Surgery
关键词
胃肠道间质肿瘤
消化系统外科手术
手术后并发症
Gastrointestinal stromal tumors
Digestive system surgical procedures
Postoperative complications
