摘要
目的了解静息心率对冠心病患者血管重建死亡率的影响。方法DESIRE-plus（Drug-Eluting Stent Impact on Revascularization plus）为单中心回顾性注册研究,入选2004年7月1日至2005年9月30日在我院接受血管重建治疗（PCI和CABG）的冠心病患者3 632例,根据入院时静息心率（RHR）分为RHR〈70次/min、70~79次/min、80~89次/min和≥90次/min四组。记录患者临床特点、住院和随访期间死亡率。
Objective To explore the prognostic value of resting heart rate （RHR） in patients with coronary heart disease （CAD） after revascularization. Methods The DESIRE-plus （ Drug-Eluting Stent Impact on Revascularization -plus） was a single-center registry study of 3 631 patients who had coronary revascularization in our institution between 1 July 2004 and 30 September 2005. The patients were followed up by telephone after discharge. We obtained risk estimates for four groups as RHR： 〈 70 bpm （reference）, 70 -79 bpm, 80 -89 bpm and≥90 bpm. Results The median follow up time was 555 days （range from 7 to 879 days）. Thirty one patients （0.9%） died during hospitalization and fifty-nine patients （1.8%） died during the follow up period. Patients with RHR≥90 bpm had a higher comorbidity rates of hypetension, diabetes mellitus, multiple vessels diseases and higher blood total cholesteral level （P 〈 0. 001 ）. All-cause mortality was increased with increasing heart rate shown by Cox regression test （P 〈 0. 001 ）. Patients with resting heart rate≥90 bpm at basdine had a significantly higher risk for total mortality （HR 3. 14, 95% CI 1.52 - 6. 49, P = 0. 002 ） after adjustment for multiple clinical variables when compared with patients with RHR 〈 70 bpm. Conclusion High resting heart rate is a predictor for total mortality independent of other risk factors in patients with CAD after revascularization.
出处
《中国介入心脏病学杂志》
2008年第3期150-154,共5页
Chinese Journal of Interventional Cardiology
关键词
心率
冠状动脉疾病
心肌血管重建术
危险因素
预后
Heart rate
Coronary disease
Myocardial revascularization
Risk factors
Prognosis
