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儿童念珠菌感染138例临床特征分析 被引量:7

Clinical features of 138 children with Candida infection
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摘要 目的了解儿童念珠菌感染的临床特征。方法回顾性分析2003-2005年138例念珠菌培养阳性的住院儿童的临床资料。按11∶比例选择年龄和性别相似、同期住院的念珠菌培养阴性患儿作为对照。危险因素分析应用SAS6.12统计软件计算。结果3年念珠菌培养阳性率分别为0.43%、0.50%和0.79%。气管内吸出物和支气管肺泡灌洗液(BALF)培养阳性34例(24.6%),深部鼻咽吸出物培养阳性94例(68.1%),血培养阳性10例(7.2%)。气管插管机械通气25例(18.1%);静脉插管13例(9.4%);全静脉营养11例(8.0%)。抗生素使用率为100%,平均使用种类为(3.03±1.89)种;第三代头孢菌素使用率56.7%。抗生素平均使用时间15.5 d。使用全身糖皮质激素33例(23.9%)。结论儿童念珠菌感染的发病率有所增加。秋冬季阳性率较高可能与儿童呼吸道疾病发病率增高和环境真菌数量增多有关。粒细胞减少症、营养不良等基础疾病,广谱抗生素、糖皮质激素和侵入性诊疗措施等均为念珠菌感染的危险因素。
出处 《临床儿科杂志》 CAS CSCD 北大核心 2008年第6期492-495,共4页 Journal of Clinical Pediatrics
关键词 儿童 念珠菌 临床特征 children Candida clinical features
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参考文献12

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