摘要
目的比较奎硫平及氯氮平对精神分裂症患者认知功能的影响。方法对60例精神分裂症患者随机分成两组,分别给予奎硫平、氯氮平治疗8周,治疗前和治疗8周末分别进行简明精神病评定量表(BPRS)、韦氏成人记忆量表修订本(WMS-RC)威斯康星卡片分类测验(WCST)和数字划销测验(CT)评定,分别评定其认知功能和临床疗效。结果两组治疗8周后,各项检查项目均有显著好转。结论奎硫平和氯氮平均能明显改善精神分裂症患者的认知功能,相比较而言奎硫平更优。
Objective To compare the effects between queitapine and clozapine on cognitive function in schizophrenics. Methods Sixty cases of schizophrenia patients were randomly divided into two groups and treated with queitapine or clozapine for 8 weeks. The cognitive function and clinical efficacy were evaluated separately with brief psychiatric rating scale（BPRS） ,WMS-RC, WCST and CT before treatment and at the end of the eighth week of treatment. Results The total score of every test was significantly improved after trentment with queitapine or clozapine, but no significant differences were found between two groups. Conclusion Both queitapine and clozapine can improve the congnitive function in schizophrenic patients.
出处
《中国实用医药》
2008年第18期61-62,共2页
China Practical Medicine
关键词
奎硫平
氯氮平
精神分裂症
认知功能
Queitapine
Clozapine
Schizophrenia
Congnitive function
