摘要
目的探讨Rh母子血型不合新生儿溶血病检测新方法——单核单层检测。方法采集Rh抗体阴性对照组和阳性组共30例孕妇的血液标本,分别采用血清抗体鉴定和单核单层检测两种方法进行检测并比较。结果单核单层检测的灵敏度为77.8%,特异性为90.5%,阴性预示值为90.5%,阳性预示值为77.8%,准确率为86.7%。结论单核单层检测作为Rh系统新生儿溶血病诊断的辅助手段,有利于该病的早期诊断和及时治疗。
Objective To investigate the novel method monocyte monolayer assay for detecting Rh maternofetal blood group incompatible hemolytic disease of the newborn. Methods Blood samples were collected from 9 cases of Rh antibody negative pregnant women and 21 cases of Rh antibody positive ones. Serum antibody identification assay and monocyte monolayer assay were adopted, and the results were compared. Results The research showed that the sensitivity of monocyte monolayer assay was 77. 8%, the specificity was 90. 5%, the negative predicted value was 90. 5%, the positive one was 77.8%, and the accuracy was 86. 7%. Conclusion As a kind of assistant method for diagnosing Rh maternofetal blood group incompatible hemolytic disease of the newborn （HDN）, monocyte monolayer assay is helpful for the early diagnosis and for Rh haemolytlc disease of the newborn,it is beneficial for the early diagnosis and prompt therapy of HDN.
出处
《国际检验医学杂志》
CAS
2008年第6期496-497,500,共3页
International Journal of Laboratory Medicine
